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FIGURE 3 2.2 Pulmonary fibrosis Pulmonary fibrosis (PF) is an aberrant ECM deposition and excessive fibroblast accumulation that causes a chronic, progressive alveolar illness (Strieter and Mehrad, 2009)

Using sterile water in a multi-dose vial creates a contamination risk once the stopper is punctured

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Results GEP44 binds to and activates GLP-1R, Y1-R, and Y2-R via biased agonism The addition of GEP44 to H188-GLP-1R transduced HEK293 cells resulted in elevated levels of cAMP with an EC 50 value of 417 pM (Fig